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Background: Incretins were discovered after it was observed that administration of an oral glucose load leads to a much greater stimulation of insulin release than a comparable glucose load given intravenously (Hansotia & Drucker, 2005)

Up to now, powerful genetic tools allowed clarification of the significance, dispensability and potential of cystine transporters for ferroptotic cell death in PDAC and breast cancer (16, 28)

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Ultimately, the integration of functional food active ingredients into comprehensive cancer care may offer novel, safer, and more personalized approaches to oncologic treatment and prevention