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The therapy remains investigational and unavailable outside clinical trials, and it requires specialized endocrinology monitoring due to risks of pancreatitis and gallbladder complications

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PMID: 33838123

CARD9-deficient patients have limited efficacy to conventional antifungal drugs such as azoles and echinocandins, and require prolonged treatment courses or combined immunomodulatory therapy

What makes 5-Amino-1MQ especially promising is its ability to selectively target adipose (fat) tissue without affecting muscle tissue, making it an intriguing option for weight management and overall metabolic support