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The TCORS 2023 program includes three separate projects: Translational Studies on Temperature and Solvent Effects on Electronic Cigarette-Derived Oxidants (PIs: Zachary Bitzer and Thomas Spratt) Oxidative Stress and Harmful Constituent Levels Associated with Little Cigars (PI: Joshua Muscat) Randomized Placebo-controlled Trial of Nicotine Pouches in Smokers (PIs: Jonathan Foulds and Jason Robinson, University of Texas MD Anderson) A component of each of the TCORS grants is to incorporate training and funding opportunities for early career, non-tenured scientists interested in pursuing tobacco regulatory science research