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Its chemical stability and rapid intestinal absorption overcome the inherent limitation of free butyrate, including short plasma half-life and failure to achieve therapeutic concentrations in target tissues

Sometimes considered as the male equivalent of female menopause, the age-related clinical and biochemical syndrome in men is also termed as andropause [5], late-onset hypogonadism (LOH) [6], symptomatic late-onset hypogonadism (SLOH) [7], male climacteric, viropause, androgen deficiency in aging males (ADAM) [8], partial androgen deficiency in aging male (PADAM), and testosterone deficiency syndrome (TDS) [9]

while the SHAM group was exposed to air during the same period of time as previously described (Al-Odat et al., , 0.1 mg/g, i.p., Abbott Australasia Pty