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Both in vivo and in vitro studies have shown that Hcy can induce ECs pyroptosis and release of inflammatory factors such as IL-1 and IL-18 via caspase-1-dependent inflammasome activation through the accumulation of intracellular ROS (76)

Immunological status of the stomach in inflammatory bowel diseasecomparison between ulcerative colitis and Crohns disease

Mesenteric adipose tissue B lymphocytes promote local and hepatic inflammation in nonalcoholic fatty liver disease mice

Third, the reversible epigenetic modifications and short-lived memory effects of trained immunity offer promising intervention points

Blood 138 , 898911 (2021)