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When examining the 2013-USPSTF criteria using raw extracted data without rule-based smoothing, the associations exhibited wider confidence intervals and no significant association (Supplemental Fig

We cant attribute this increase to the smoking habit alone because this was an observational (case-control) study rather than a randomized experiment, though they did match age and economic factors between the two groups

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population studies to work out their findings: the British Doctors Study and the Million Women Study

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