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J Anal Toxicol 38:569574 Desrosiers NA, Himes SK, Scheidweiler KB et al (2014) Phase I and II cannabinoid disposition in blood and plasma of occasional and frequent smokers following controlled smoked cannabis

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In the first stage, eligibility criteria included: 1) consume at least ten conventional cigarettes a day, a criterion chosen to target smokers who are likely to experience intense withdrawal symptoms during temporary abstinence 19