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Administration Routes subcutaneous Range 210 mcg/kg body weight/day animal studies (rat models) Administration Routes oral Range 10 mcg/kg body weight/day animal studies (rat models, gastrointestinal endpoints) Reconstitution Calculator Determine exactly how much bacteriostatic water to add and how many units to draw for your target dose

Statistical analysis Statistical analysis was performed by parametric one-way ANOVA with post hoc Newman-Keuls test and non-parametric Kruskal-Wallis and subsequent Mann-Whitney U -test to compare groups

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To determine if GDC directly inhibits PKA, GDC solutions were incubated directly with cAMP in the absence of cells