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This process may gradually shift the production of darker eumelanin toward lighter pheomelanin

doi: 10.1016/j.freeradbiomed.2019.03.027 160 IrimiaTPucaiuLMitranoviciM-ICrianABudianuMABnescuCet al

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While pharmacologic inhibition may not induce enough inhibition, G6PD knockdown may go too far, and neither recapitulates the protein instability that is characteristic of human G6PD-d