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A low ratio may reflect inflammation, cellular aging, or toxin exposure

Inhaled mRNA therapy for treatment of cystic fibrosis: interim results of a randomized, double-blind, placebo-controlled phase 1/2 clinical study

Such a setup would precisely delineate the NSC-derived paracrine factors (e.g., BDNF, VEGF [18, 32], TGF-) responsible for suppressing microglial activation and promoting an anti-inflammatory phenotype, independently of in vivo complexities

doi: 10.1007/s12035-018-1096-7 222 KennedyPJCryanJFDinanTGClarkeG

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