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As recently pointed out by the Flavor and Extracts Manufacturers Association (FEMA), while many of the flavor chemicals used in EC refill fluids are on the FEMA GRAS (generally regarded as safe) list, the GRAS designation presumes ingestion and does not apply to inhalation 14,15

Perceived impact on own/others smoking behavior Participants generally felt it unlikely that inserts would prompt them to change their smoking behavior

You wouldnt typically compare a 20mg freebase to a 20mg nic salt as equivalent experiences the delivery is meaningfully different

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Both stories stated that this suggestion came from a source within the UKs Department of Health