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Incidence of Seizure with Bupropion Use When bupropion hydrochloride extended-release (SR) tablets are dosed up to 300 mg/day, the incidence of seizure is approximately 0.1% (1/1,000) and increases to approximately 0.4% (4/1,000) at the maximum recommended dose of 400 mg/day

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They might even be present in low levels in common foods and drinks such as baked goods, cured meats, and a few fruit juices

Several fatal cases have been under forensic investigation, most of these were mixed poisonings, but a few pure fatal Spice intoxications have occurred

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