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Thereby, in ketamine-rat, BPC 157 therapy was able to affect all negative-like symptoms in the same way (i.e., BPC 157 counteracts cognition deficit, social withdrawal, anhedonia and has an additional anxiolytic effect), L-arginine and L-NAME could ameliorate some but worsen others [59]

How Their Mechanistic Strategies Differ Selective-receptor strategy In addition, eloralintide is explicitly designed around preferential AMY1 receptor activation with reduced calcitonin-receptor signaling in human in-vitro systems