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Histiocytic disorders

Cortistatin: Cortistatin safety data is limited to preclinical models

Specifically, its an NNMT inhibitor. Lets unpack what that means, because the name sounds scarier than the idea

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With BPC 157 therapy, given as local bath at the swollen brain, but also intraperitoneal and intragastric application, g- and ng-regimens, at 1 min, 15 min, 24 h or 48 h ligation-time, the increased (positive) pressure in the superior sagittal sinus is immediately reversed to the normal (negative) pressure