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Preclinical animal studies further validate its neuroprotective potential: phillyrin A improves learning and memory in senescence-accelerated mice, activates the Nrf2 signaling pathway in APP/PS1 mice, upregulates antioxidant proteins (NQO1, GPX4), and normalizes cerebral iron content through modulation of TFRC, DMT1, FTH, and FTL gene expression (234)

Based on the 3/S ( and S are the standard deviation of 10 parallel blank measurements and the slope of the linear fitting equation, respectively), the LOD was 0.018 g/mL

Birchmeier, Sonnenberg et al

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What Is GHK-Cu, Really