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In contrast to EAE where the primary stimulus is immune upregulation in the presence of extrinsic myelin antigens, the CAE model illustrates that MS-like pathology can also be generated by an upstream intrinsic myelin injury, releasing antigens which secondarily trigger white matter inflammation in an immune-predisposed host

doi: 10.1073/pnas.0709747104 146 NicodemeEJeffreyKLSchaeferUBeinkeSDewellSChungC-wet al

Staphylococcus aureus : new evidence for intracellular persistence

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Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide), also known by its developmental code PNB-0408, is a synthetic oligopeptide developed by researchers at Washington State University as a metabolically stable derivative of angiotensin IV