Boonyaritichaikij S, Kuwabara K, Nagano J, Kobayashi K, Koga Y (2009) Long-term administration of probiotics to asymptomatic pre-school children for either the eradication or the prevention of Helicobacter pylori infection
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Treatment upregulated protein translation components and stimulated the transsulfuration pathway for oxidative stress protection, with no reported adverse events (Dimet-Wiley et al., 2024)
Laboratory applications explore the development of combination approaches that target multiple senescence mechanisms simultaneously, while research into biomarkers of senescent cell burden and senolytic administration efficacy enables better experimental monitoring and outcome assessment
Scientists suspect that autoimmunity underlies this condition, and an autoantibody correlating with psoriatic arthritis (anti-carbamylated protein) has recently been described (Chimenti 2015)