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In the current study, tissue staining showed a decrease in lipid deposition in the liver via L-carnitine administration

Short N, Kantarjian H, Ravandi F, Huang X, Jain N, Sasaki K, Khouri R, Daver N, Pemmaraju N, Khoury J, Jorgensen J, Alvarado Y, Konopleva M, Garcia-Manero G, Kadia T, Yilmaz M, Borthakur G , Burger J, Kornblau S, Wierda W, DiNardo C, Ferrajoli A, Jacob J, Rostykus M, Garris R, Ward M, Huang B, Encarnacion C, Loiselle C, O'Brien S, Jabbour E

Glutathione works by suppressing melanin production, helping fade dark spots, pigmentation, and uneven tone

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It will then systematically discuss the upstream regulatory mechanisms of GPX4 in the context of OA, including the System Xc and nuclear factor erythroid 2-related factor 2(Nrf2) signaling pathways, as well as its downstream biological effects, such as impacts on chondrocyte survival, inflammatory responses, and ECM metabolism