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If the excursion was brief (under 6 hours) and temperature remained below 20C, the peptide may retain partial potency, but this introduces unacceptable variability into experimental protocols

Carbamazepine exerts a use-dependent sodium channel block that preferentially blocks channels that are actively firing (blocking the fast inactivation state)

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To study the menstrual cycle in vitro, endometrial organoids are subjected to in vivo mimicking hormonal regimens [53, 54, 62]

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