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Xiu Z, Li Y, Fang J, Han J, Li S, Li Y, Yang X, Song G, Li Y, Jin N, Zhu Y, Zhu G, Sun L, Li X (2023) Inhibitory effects of esculetin on liver cancer through triggering NCOA4 pathway-mediation ferritinophagy in vivo and in vitro

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Step 3: Optimization phase (weeks 3-8) Based on assessment results, establish your working protocol: Dose: Your minimum effective dose (typically 75-200mcg) Frequency: 3-5 times weekly based on tolerance observations Timing: Your optimal pre-bedtime window Track results weekly and make minor adjustments as needed