While S in soluble proteins is estimated to be 6 to 10 times greater than the glutathione pool in optimal conditions (Queval et al., 2009), the difference can be shifted in oxidative stress conditions
Rapid evaluation of intestinal paracellular permeability using the human enterocytic-like Caco-2/TC7 cell line
What to avoid when taking glutathione To get the most from glutathione, it helps to reduce the things that deplete it: Alcohol heavily depletes glutathione and burdens the liver Smoking a major source of oxidative stress Excess processed and fried food increases free-radical load Poor sleep and chronic stress both lower natural production There aren't many strict "don't combine with X" rules for healthy adults, but if you take regular medication, have a medical condition, or are pregnant or breastfeeding, talk to your doctor first (see disclaimer below)
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Namely, sulfur has been found to attract all the negative elements, including free radicals, heavy metals, and mercury like a magnet - hence the detoxifying, health-preserving effect of glutathione
