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Despite the favorable results of transplant, organ availability is less than the demand, and up to 15% of patients listed for transplant drop out because of tumor progression before an organ becomes available

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In this process, microglia are considered important participants, and knockdown of ACSL4 can restrain the production of proinflammatory cytokines in microglia, such as TNF, IL-6, and IL-1 (Cui et al

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