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Proal and Van Elzakker, 2021
The primary function of glutathione is defence and detoxification, while NAD+ is responsible for energy production and DNA repair
How this is achieved in fungi capable of gliotoxin, BmGT and EGT biosynthesis (Sheridan et al., 2016), all of which are highly dependent on SAM utilization, and concomitant SAH generation ( Gliotoxin Biosynthesis De novo gliotoxin biosynthesis occurs as follows: Phenylalanine and serine are condensed by the non-ribosomal peptide synthetase GliP ( (1) (Figure 3)
In addition to selenium, studies in vitro on the effect of other antioxidant agents provided, at least in part, interesting results which, unfortunately, have not been yet completely confirmed by clinical studies