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There are two 2HG enantiomers: D-2-hydroxyglutarate (D2HG) and L-2-hydroxyglutarate (L2HG), with the former predominantly generated from IDH1 mutants and PHGDH while L2HG is primarily generated from the promiscuous activity of LDHA and MDH1/2 under hypoxic or acidic conditions and converted back to 2OG by L2HGDH

Models underestimate measured ambient concentrations of many organic acids, suggesting an [] 4/10/18 at 4:00 pm in Chemistry A101 4/9/18 at 12:00 pm in Chemistry A103 4/6/18 at 4:00 pm in Chemistry A101 4/5/18 at 4:00 pm in Chemistry A101 4/3/18 at 4:00 pm in Chemistry A101 Since the pioneering alkane activation work by Shilov in the early 1970s, the detailed mechanism of electrophilic methane to methanol conversion by Pt(II) salts has remained an unresolved issue

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Klotho inhibits unilateral ureteral obstruction-induced endothelial-to-mesenchymal transition via TGF-1/Smad2/Snail1 signaling in mice