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showed that changes in SDC-1 mechanical tension generate a tension gradient in SDC-1 under fluid shear force, with SDC-1 interacting differently with the cytoskeleton depending on substrate stiffness, affecting integrin-mediated signaling and focal adhesion formation [49]

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This amplified support for neuroplasticity translates into a superior capacity for learning, memory encoding, and cognitive flexibility, exceeding what either compound could achieve alone