It is mostly inflammation and water retention, caused by alcohol's effect on your hormones, your gut, and your hydration
as another control, the study could have used nicotine-free flavored vaping solutions to determine the effects of "volatile organic compounds", various "flavours", and metallic and other contaminants
Image from Felix Khusid Himrod Medicinal Cigarettes Himrod Medicinal Cigarettes (1930s-1940s) claimed to provide "temporary relief from the paroxysms of bronchial asthma." The cigarettes, manufactured in Brooklyn, New York by Himrod Mfg, Inc., contained sramonium, saltpetre, anise oil, and cedar oil
Finding Silver Coins or Knives=Receiving revelation knowledge, soul lost through sin
You may have already heard the terms MTL or DL