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Table 1 lists 46 compounds that displayed statistically significant ( 1.5x) shifts in abundance during 58 hr of fasting, whose calculated formal powers were shown in Table S2: among 46 metabolites, the statistical power for 38 compounds was found to be rather high (more than 0.8)

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Avidin and its derivatives have four biotin-binding sites per molecule so, theoretically, saturated avidin could form tetramers of biotinylated protein

10.1038/ajh.2012.20 234