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PMID 16427183

2+ ] i , iNOS, and COX 2 activation, as well as production of NO, underpin the Panx1 channel-dependent release of ATP in LPS-stimulated microglia (Orellana et al., 2013), whereas NO-mediated Cx43 s-nitrosylation is pivotal in the activation of astroglial hemichannels triggered by oxidative stress (Retamal et al., 2006)

Awareness regarding the effect of drugs of abuse on BBB integrity is paramount due to their toxic effects, which could induce immune reactions and neurodegeneration

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doi: 10.1164/rccm.201702-0405CP 31 NucktonTJAlonsoJAKalletRHDanielBMPittetJFEisnerMDet al