Cell culture The following cell lines were used in this study: IMR90 and WI-38 human fetal lung fibroblasts (female), BJ human foreskin fibroblasts (male), NIH3T3 mouse fibroblasts, wt and bax/bak / littermate Baby Mouse Kidney (BMK) cells, Human Embryonic Kidney (HEK) 293LTV
Use lightly at first
As of September 2023 it is on the FDA's Category 2 list of bulk drug substances that may not be compounded due to significant safety risks, and the agency has scheduled a Pharmacy Compounding Advisory Committee (PCAC) review for July 2026 covering proposed uses in opioid withdrawal, chronic insomnia, and narcolepsy
That's where AHK-Cu becomes synergistic: growth hormone peptides stimulate procollagen production, and AHK-Cu provides the copper required for lysyl oxidase to cross-link that procollagen into stable, mature collagen fibers
Conze D, Brenner C, Kruger CL