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The elucidation of cuproptosis as a mechanism connecting inflammatory, metabolic, and mitochondrial damage to cardiomyocyte death opens new therapeutic avenues

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Moreover, LOXL1 is expressed in major organs in late fetal and neonatal mice, but it generally diminishes in aging animals, which may be associated with aortic fragility resulting from abnormal remodeling of collagen and elastic fibers (Hayashi et al., 2004

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