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105 These findings imply that oxidized POLG causes mtDNA mutation or depletion and in turn results in a variety of diseases

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Arch Biochem Biophys 595:1924 Taetzsch T, Levesque S, McGraw C, Brookins S, Luqa R, Bonini MG, Mason RP, Oh U et al (2015) Redox regulation of NF-B p50 and M1 polarization in microglia

Since the brain needs to metabolise glucose, any precious glucose consumed or stored as glycogen in other tissues could be seen as problematic

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