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Imidazole is a planar, five-membered, unsaturated, 6 electron ring system, comprised of three carbon atoms and two nitrogen atoms at 1,3-positions with two olefinic bonds
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This mechanism explains why many users report feeling a "clean" energy boost without the heart palpitations associated with stimulants
Other markers are not commonly measured either in clinical practice or in many clinical trials, making it difficult to interpret whether positive outcomes in some studies are due to correcting a deficiency or due to other pharmacological functions of B12
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