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The ATG12-ATG5-ATG16L1 complex drives membrane expansion (18), whereas microtubule-associated protein 1 light chain 3 (LC3) is conjugated to phosphatidylethanolamine, converting LC3-I to membrane-bound LC3-II, a hallmark of autophagosomes (19)

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i , Relative RPKM values of SLC25A39, FTL and HBB genes in human erythroblasts at differing stages of terminal differentiation