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Since the 1980s, in addition to its licensed indications as a mucolytic and an antidote to acetaminophen overdose, the therapeutic potential of NAC has been investigated in a wide range of conditions where oxidative stress is thought to be a driving factor in disease onset and/or progression [9]

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J Biol Chem 279:1624616253

Samsun) displayed high levels of GSH following e.g., herbicide exposure and enhanced activities of GST associated with reduced development of HR caused by Tobacco necrosis virus (TNV) (Gullner et al., Tobacco mosaic virus (TMV) inoculation was preceded by a transient drop in antioxidant enzyme activities, e.g., APX, glutathione reductase (GR) and GST