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[DOI] [PubMed] [Google Scholar] Ting JT, Feng G
OneBlood, Orlando, FL and Vitalant Research Institute, Denver CO
In NSCLC, MEG3 suppresses tumor proliferation and metastasis via the miR-21-5p/PTEN and MDM2/p53 axes, while in pulmonary hypertension, it promotes vascular remodeling by sponging miR-328-3p and upregulating IGF1R, highlighting its dual context-dependent roles in tumor suppression and vascular dysfunction [109,110,111]
An antioxidant protector that shields your cells from oxidative stress during illness or intense physical activity